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My children are 22 1/2 months apart. It worked great for our family. I did find potty training my daughter with a newborn was a little difficult. Potty training is just so time consuming. There were some jealousy issues in the begining especially when my son started moving around. My daughter out grew that in a couple of months. She is now 3 and my son 1 1/2 yrs old and they play amazingly together (some fighting in between as can be expected) but you can see the love in my daughter's eyes.
My boys are 3 1/2 years apart and we love it!! We always wanted 3-4 years between our kids so we could spend quality time with our first child. It worked great too when our second was born... our oldest could dress himself, was potty trained and could actually be a helper. While I was taking care of the baby, he was self sufficient enough to play on his own and do his thing throughout the house.
They are 5 & 2 now and there are times they are best friends and times where they both just want to be on there own, no different than any other siblings. You don't need to have them close together for them to be best friends :-)